• Association of low-density lipoprotein cholesterol with risk of aortic valve stenosis in familial hypercholesterolemia 

      Mundal, Liv; Hovland, Anders; Igland, Jannicke; Veierød, Marit Bragelien; Holven, Kirsten Bjørklund; Bogsrud, Martin Prøven; Tell, Grethe S.; Leren, Trond Paul; Retterstøl, Kjetil (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-16)
      <i>Importance</i> - Aortic valve stenosis (AS) is the most common valve disease. Elevated levels of low-density lipoprotein (LDL) cholesterol are a risk factor; however, lipid-lowering treatment seems not to prevent progression of AS. The importance of LDL cholesterol in the development of AS thus remains unclear. People with familial hypercholesterolemia (FH) have elevated LDL cholesterol levels ...
    • Risk of Ischemic Stroke and Total Cerebrovascular Disease in Familial Hypercholesterolemia 

      Hovland, Anders; Mundal, Liv; Igland, Jannicke; Veierød, Marit Bragelien; Holven, Kirsten Bjørklund; Bogsrud, Martin Prøven; Tell, Grethe S.; Leren, Trond Paul; Retterstøl, Kjetil (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-21)
      <p><i>Background and Purpose</i>: Familial hypercholesterolemia (FH) is a common autosomal dominant disease leading to increased level of serum LDL (low-density lipoprotein) cholesterol and risk of coronary heart disease. Whether FH increases the risk of cerebrovascular disease, including ischemic stroke, is debated. Accordingly, we studied the incidence of cerebrovascular disease in a cohort of ...